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Amyotrophic lateral sclerosis (ALS) is characterized by the degeneration of both upper and lower motor neurons, which ultimately leads to muscle weakness, atrophy, spasticity and contractures.1 ALS typically manifests in the 50–60 years age range, although familial cases may present in late adolescence or early adulthood.2 The time from the first symptom to diagnosis is approximately 10–16 […]

Edwin B George, AAN 2018 – Multiple system atrophy (MSA) diagnosis

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Published Online: May 9th 2018

Edwin George (Wayne State University, MI) explains why the diagnosis of multiple system atrophy (MSA) is so challenging and what is known in terms of causes of the condition.

Questions

1. Why is the diagnosis of multiple system atrophy (MSA) so challenging? (0:11)
2. Are there any known causes of MSA? (2:39)

Speaker disclosure: Edwin George is a pro bono advisor on Defeat MSA’s scientific and medical board. He also delivers disease awareness talks for Lundbeck Pharmaceuticals.

Filmed at the American Academy of Neurology (AAN) Annual Meeting 2018, Los Angeles, CA, US, April 2018.

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