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The prevalence of unruptured intracranial aneurysms (IAs) is approximately 3% of the population, with incidence on the rise due to the increased utilization of neuro-imaging for diverse objectives.1,2 The average risk of rupture for unruptured IA is estimated to vary from 0.3% to exceeding 15% per 5 years.3 Ruptured IA is the primary aetiology of […]

Anthony Béhin, EAN 2023: Safety Profile Overview of Efgartigimod Clinical Trials in Participants With Diverse IgG-Mediated Autoimmune Diseases

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Published Online: Jul 28th 2023

Dr Anthony Béhin (University Hospitals Pitié Salpêtrière, Paris, France) discusses his abstract on the safety profile of anti-FcRn drugs, in particular efgartigimod, and anti-complement drugs in the treatment of IgG-mediated autoimmune diseases.

The abstract ‘EPR-128 Safety Profile Overview of Efgartigimod Clinical Trials in Participants With Diverse IgG-Mediated Autoimmune Diseases’ was presented at the annual European Academy of Neurology (EAN), July 1–4, 2023

Questions

1. Please can you summarize the safety profile of anti-FcRn drugs, in particular efgartigimod, in IgG-mediated autoimmune diseases (00:26)
2. Please summarize the safety and efficacy profile of anti-complement drugs in the treatment of IgG-mediated autoimmune diseases (04:42)

Disclosures: Anthony Béhin is a consultant for Alexion, Argenx, UCB, Sanofi and Ultragenyx pharmaceutical. He has received grant/research support from the Association Institut de Myologie and is on the advisory board for Alexion, Argenx, UCB, Sanofi and Ultragenyx pharmaceutical. He has received honoraria/honorarium from Alexion, Argenx, UCB, Sanofi and Ultragenyx. pharmaceutical

Support: Interview and filming was supported by Touch Medical Media. The interview was conducted by Sophie Nickelson.

Filmed as highlight of EAN 2023.

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