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Mechanical thrombectomy: Evidence basis and future directions

Abdelmageet Hassan, Sumanjit Gill

Both intracerebral hemorrhage and ischemic stroke continue to be the leading causes of disability and the second leading causes of death worldwide.1,2 The burden is largest in low- and middle-income countries, which have seen rapid recent population growth. Large vessel occlusion (LVO – internal carotids, vertebrals and the proximal branches of the circle of Willis) accounts for 20% of all acute ischemic strokes (AISs) […]

touchREVIEWS in Neurology. 2026;22(1):Online ahead of journal publication

Headache Disorders

Migraine Headaches and SGB Treatment

Published Online: Aug 22nd 2014

Dr. David James discusses a new procedure for those who suffer from migraine headaches.

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Headache disorders at EAN24: Developments and the future

Peter J Goadsby

Data from the REFORM trial (NCT04674020) provide valuable insights into cortical inflammation in adults with migraines, using a novel quantitative, multimodal MRI technique to compare these patients with age- and gender-matched healthy controls, enhancing our understanding of migraine biology and other headache disorders. The discussion also covers cluster headaches, focusing on a study that examines premonitory symptoms in affected individuals and highlights key phenotypic characteristics. Additionally, we explore findings from the European Migraine & Headache Alliance on the stigma surrounding migraines, which yield insightful and actionable results. Looking ahead, the focus shifts to the latest data on new medications for preventing and treating migraine attacks, discussing future prospects and identifying areas in headache disorder management that still need further attention.

Related Videos in Headache Disorders

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Peter Goadsby, EAN 2023: Highlights in migraine

In this touchNEUROLOGY interview, editorial board member Prof Peter Goadsby (King's college Hospital, London) highlights two presentations from the annual European Academy of Neurology (EAN), July 1–4, 2023, in the field of migraine; the first by Klein et al. looking at a ...

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Peter Goadsby, EAN 2023: Highlights in headache disorders

In this touchNEUROLOGY interview, editorial board member Prof Peter Goadsby (King's college Hospital, London) provides an overview of his top three most important clinical trial data and hot topics presented at the annual European Academy of Neurology (EAN), July 1–4, 2023, in ...

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Highlights from EAN 2023!

...

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Stewart Tepper, AAN 2023: Atogepant for the preventive treatment of chronic migraine: results from the PROGRESS phase 3 trial

Prof Stewart Tepper (Geisal School of Medicine - Dartmouth, Hanover, NH, USA) summarizes the pivotal results of the PROGRESS phase 3 trial, evaluating the efficacy, safety, and tolerability of atogepant for preventive treatment of chronic migraine (CM). This study has very ...

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Atogepant for preventive treatment of chronic migraine, PROGRESS phase 3 trial: Richard Lipton, AAN 2023

Atogepant represents a relatively new class of medications called CGRP receptor antagonists, which have shown efficacy in preventing migraines. The PROGRESS phase 3 clinical trial assessed the efficacy of atogepant, an important new oral treatment option for the 8% of people with ...

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Stewart Tepper, AAN 2023: Results from the PRODROME trial of ubrogepant for the acute treatment of migraine

Prof Stewart Tepper (Geisal School of Medicine - Dartmouth, Hanover, NH, USA) shares one the most exciting presentations from the 75th AAN Annual Meeting, 2023. The results of the PRODROME study represent a paradigm shift in headache management and the data ...

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Stewart Tepper, AAN 2023: Significant reduction in migraine days with REN for migraine prevention: A double-blind randomized sham-controlled clinical trial

Migraine affects over 1 billion people worldwide causing significant disability and a socioeconomic burden. Preventive treatment is key to managing migraine, but it is often underutilized. Prof Stewart Tepper (Geisal School of Medicine - Dartmouth, Hanover, NH, USA) summarizes his presentation ...

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Stewart Tepper, AAN 2023: Phase 3 ASCEND interim analysis - STS101 for the treatment of acute migraine

Prof Stewart Tepper (Geisal School of Medicine - Dartmouth, Hanover, NH, USA) summarizes safety and tolerability data from the ASCEND study of STS101 5.2 mg (dihydroergotamine nasal powder) in the acute treatment of migraine attacks with/without aura over 12 months. STS101 ...

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Stewart Tepper, AAN 2023: Combination of rizatriptan and AXS-07 - results from the MOMENTUM and INTERCEPT studies

A better understanding of the key areas of unmet need regarding acute migraine therapy may help inform drug development and treatment selection. Prof Stewart Tepper (Geisal School of Medicine - Dartmouth, Hanover, NH, USA) summarizes a poster on data from ...

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Robert Music, The Migraine Trust: Improving migraine care - ensuring patient-focussed diagnosis and treatment in the UK

"Migraine is a common and complex brain disorder that affects 10 million people in the UK, impacting their ability to work, relationships and mental health. It’s poorly understood by the public and even many health professionals, and there are challenges ...

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Raquel Gil-Gouveia, EAN 2022: Highlights in headache and migraine - Treatment advances, strategies for prevention, Anti-CGRP use in migraine, COVID-19

Headache is one of the most common nervous system disorders. In an interview with touchNEUROLOGY, Dr Raquel Gil-Gouveia (Hospital da Luz, Lisbon, Portugal) summarizes the ePoster session she chaired at EAN 2022, ranging from topics such as how COVID-19 has impacted ...

Stewart Tepper

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Stewart Tepper, AAN 2022: Limitations of current treatments for acute migraine

The limitations of the current treatment of acute migraine are said to be patient variability and migraine attack variability. Prof. Stewart Tepper (Dartmouth-Hitchcock Medical Centre, Lebanon, NH, USA) discusses the limitations of current treatments for acute migraine and how new ...

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