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Motor neuron synapses with muscle fiber via electrical impulse transmission and neurotransmitter release, forming neuromuscular junctions , motor neuron, neuroscience
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Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder of upper and lower motor neurons that results in progressive motor impairment. ALS is the most common disease of motor neurons with an annual incidence of approximately 1.7–2.5 per 100,000 people. It is a terminal condition with a typical life expectancy of 2–5 years from symptom onset. […]

Edwin B George, AAN 2018 – Multiple system atrophy (MSA) management

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Published Online: May 9th 2018

Edwin George (Wayne State University, MI) discusses the limitations of current therapeutic options for multiple system atrophy (MSA), and what have been the most promising recent advances toward management of the condition.

Questions

1. What are the limitations of current therapeutic options in MSA? (0:11)
2. What have been the most promising recent advances in the treatment of MSA? (3:15)

Speaker disclosure: Edwin George is a pro bono advisor on Defeat MSA’s scientific and medical board. He also delivers disease awareness talks for Lundbeck Pharmaceuticals.

Filmed at the American Academy of Neurology (AAN) Annual Meeting 2018, Los Angeles, CA, US, April 2018.

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