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Both intracerebral hemorrhage and ischemic stroke continue to be the leading causes of disability and the second leading causes of death worldwide.1,2 The burden is largest in low- and middle-income countries, which have seen rapid recent population growth. Large vessel occlusion (LVO – internal carotids, vertebrals and the proximal branches of the circle of Willis) accounts for 20% of all acute ischemic strokes (AISs) and causes large, disabling […]

Anthony Béhin, EAN 2023: Safety Profile Overview of Efgartigimod Clinical Trials in Participants With Diverse IgG-Mediated Autoimmune Diseases

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Published Online: Jul 28th 2023

Dr Anthony Béhin (University Hospitals Pitié Salpêtrière, Paris, France) discusses his abstract on the safety profile of anti-FcRn drugs, in particular efgartigimod, and anti-complement drugs in the treatment of IgG-mediated autoimmune diseases.

The abstract ‘EPR-128 Safety Profile Overview of Efgartigimod Clinical Trials in Participants With Diverse IgG-Mediated Autoimmune Diseases’ was presented at the annual European Academy of Neurology (EAN), July 1–4, 2023

Questions

1. Please can you summarize the safety profile of anti-FcRn drugs, in particular efgartigimod, in IgG-mediated autoimmune diseases (00:26)
2. Please summarize the safety and efficacy profile of anti-complement drugs in the treatment of IgG-mediated autoimmune diseases (04:42)

Disclosures: Anthony Béhin is a consultant for Alexion, Argenx, UCB, Sanofi and Ultragenyx pharmaceutical. He has received grant/research support from the Association Institut de Myologie and is on the advisory board for Alexion, Argenx, UCB, Sanofi and Ultragenyx pharmaceutical. He has received honoraria/honorarium from Alexion, Argenx, UCB, Sanofi and Ultragenyx. pharmaceutical

Support: Interview and filming was supported by Touch Medical Media. The interview was conducted by Sophie Nickelson.

Filmed as highlight of EAN 2023.

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