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Both intracerebral hemorrhage and ischemic stroke continue to be the leading causes of disability and the second leading causes of death worldwide.1,2 The burden is largest in low- and middle-income countries, which have seen rapid recent population growth. Large vessel occlusion (LVO – internal carotids, vertebrals and the proximal branches of the circle of Willis) accounts for 20% of all acute ischemic strokes (AISs) and causes large, disabling […]

José A. López García, EAN 2021: Clinical Development of SAN711, and its Potential to Treat Neuropathic Pain

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Published Online: Aug 9th 2021

It was a pleasure to meet with José A. López García (University of Alcalá, Alcalá de Henares, Spain) to discuss the clinical development of SAN711, a selective GABAA α3 receptor positive allosteric modulator for the potential treatment of neuropathic pain.

The abstract entitled: ‘SAN711 a selective GABAA α3 receptor positive allosteric modulator as a novel treatment for trigeminal neuralgia ’ was presented at the 7th Congress of the European Academy of Neurology – Virtual 2021.

Questions:

  1. Could you tell us a little about SAN711, its selectivity and mechanism of action? (0:16)
  2. What are the objectives and design of the Phase 1 study of SAN711? (8:53)
  3. What are the intended clinical indications of SAN711? (10:55)

Disclosures: José A. López García has nothing to disclose in relation to this video.

Support: Interview and filming supported by Touch Medical Media. Interview conducted by Katey Gabrysch

Filmed as a highlight of the EAN Congress, Virtual 2021

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