We heard about the interesting roles that mitochondrial dysfunction and the gastrointestinal microbiome play in Parkinson’s disease, thanks to expert insight from MDS Congress Scientific Program Committee member, Carolyn Sue (Kolling Institute, University of Sydney, Northern Clinical School; and Royal North Shore Hospital, St Leonards, New South Wales, Australia).
Questions
1. Please describe the significance of mitochondrial dysfunction in relation to the pathology of Parkinson’s disease (PD). (0:05)
2. In addition to mitochondrial dysfunction, there has been increasing interest in the gastrointestinal microbiome (GM) in PD. What do we currently know about the role of the GM in PD? (1:25)
3. How might our increased understanding of mitochondrial dysfunction and the GM in PD contribute to novel therapeutics? (2:22)
Speaker disclosure: Carolyn Sue has nothing relevant to disclose in relation to this video interview.
Filmed at the International Congress of Parkinson’s Disease and Movement Disorders (MDS), Nice, France, September 2019.
