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Both intracerebral hemorrhage and ischemic stroke continue to be the leading causes of disability and the second leading causes of death worldwide.1,2 The burden is largest in low- and middle-income countries, which have seen rapid recent population growth. Large vessel occlusion (LVO – internal carotids, vertebrals and the proximal branches of the circle of Willis) accounts for 20% of all acute ischemic strokes (AISs) and causes large, disabling […]

Roger McIntyre – Psilocybin-based Therapies in Mood Disorders

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Published Online: Jul 21st 2020

TouchNEUROLOGY caught up with Roger McIntyre (University Toronto, Ontario, Canada) to discuss psychedelics, and in particular psilocybin-based therapies, and their potential in the treatment of mood disorders.

Questions

1. Please could you give us a brief overview of psilocybin and its action on serotonergic (5-HT) pathways? (0:04)

2. Which conditions are most likely to benefit from psilocybin therapy? (0:48)

3. What are the major challenges in bringing psilocybin-based products to the market? (1:57)

4. Could you tell us a little about the products you are working with and the current research activities? (3:18)

5. What will be the next steps in the development of psilocybin-based therapies? (4:38)

Speaker Disclosure: Roger McIntyre has acted as a consultant and/or received research support from Lundbeck, Janssen, Shire, Purdue, Pfizer, Otsuka, Allergan, Takeda, Neurocrine, Sunovion, Minerva, Intra-Cellular Pharmaceuticals, Stanley Medical Research Institute, and CIHR/GACD/National Natural Science Foundation of China. He is CEO of Champignon, which acquired the Canadian Rapid Treatment Centre of Excellence.

Support: Interview and filming supported by Touch Medical Media.

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