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Motor neuron synapses with muscle fiber via electrical impulse transmission and neurotransmitter release, forming neuromuscular junctions , motor neuron, neuroscience
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Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder of upper and lower motor neurons that results in progressive motor impairment. ALS is the most common disease of motor neurons with an annual incidence of approximately 1.7–2.5 per 100,000 people. It is a terminal condition with a typical life expectancy of 2–5 years from symptom onset. […]

EUROPEAN NEUROLOGICAL REVIEW – VOLUME 14 ISSUE 2 – WINTER 2019

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3 mins
Cris S Constantinescu

Welcome to the latest edition of European Neurological Review, which features a wide range of articles of interest to neurologists and other practitioners involved in the care of patients with neurological illness. As we move into a new decade, the field of neurology continues to face fresh challenges. Despite an increased understanding of the pathophysiological […]

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Expert Interview

Therapeutic plasma exchange (TPE) has been an accepted treatment for specific neurological disorders for several decades. For some medical professionals, it is seen as an effective treatment option alongside immunomodulatory therapies and other medicines. But its benefits for patients still need to be more widely recognised among medical professionals in many countries. Recent innovations in […]

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Editorials

Seizure is a paroxysmal event caused by the excessive, hypersynchronous discharge of neurons in the brain, which causes alteration in neurologic function.1 Seizures can occur when there is a distortion between the normal balance of excitation and inhibition in the brain. The factors that cause this alteration in the balance of excitation and inhibition can […]

Migraine is the most common neurological disorder and one of the most disabling health disorders worldwide, often occurring in working age, and in young adult and middle-aged women.1 It is a debilitating condition that is hard to treat, can last anywhere from 4 hours to 3 days and has a substantial negative impact on quality […]

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Reviews

15 mins
Beyza Ciftci-Kavaklioglu, E Ann Yeh

Multiple sclerosis (MS) is an inflammatory disease of the central nervous system affecting almost 3 million individuals worldwide.1–3 The precise pathogenesis of the disease is unknown, though migration of peripheral T and B lymphocytes into the central nervous system is considered to be one of the major pathophysiologic mechanisms.4–6 Sphingosine-1-phosphate (S1P) modulators, through induction of […]

Myasthenia gravis (MG) leads to muscle weakness, which increases with repetitive use of muscles; in the morning, many patients are symptom-free.1,2 Diplopia, ptosis and weakness in other muscles innervated by cranial nerves, are typical. The muscle weakness is, in most patients, generalised with weakness also in the extremities, and sometimes in respiratory muscles. Muscle weakness […]

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European Neurological Review is a peer-reviewed, free-to-access, bi-annual neurology journal comprising review articles, case reports, practice guides, theoretical discussions, and original research. It features balanced and comprehensive articles written by leading authorities, addressing the most important and salient developments in the field of neurology in practical terms.

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