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The prevalence of unruptured intracranial aneurysms (IAs) is approximately 3% of the population, with incidence on the rise due to the increased utilization of neuro-imaging for diverse objectives.1,2 The average risk of rupture for unruptured IA is estimated to vary from 0.3% to exceeding 15% per 5 years.3 Ruptured IA is the primary aetiology of […]

Kimford Meador, AAN 2021: Fetal Antiseizure Medication in Pregnant Women with Epilepsy

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Published Online: Apr 23rd 2021

It was a great pleasure to meet with Kimford Meador (Stanford University, Stanford, CA, USA) to discuss the effects and use of antiseizure medications during pregnancy, in women with epilepsy.

The abstract entitled: ‘Fetal Antiseizure Medication Effects on Neuropsychological Outcomes at Age 3 Years in the MONEAD Study’ was presented at the American Academy of Neurology Virtual Annual Meeting 2021.

Questions:

  1. What is known about the risks to children born to women who use antiseizure medications (ASMs) during pregnancy? (0:16)
  2. How does pregnancy affect seizure frequency and the need for ASMs? (2:37)
  3. What is known about the changes in clearance rates of ASMs during pregnancy? (3:40)

Disclosures: Kimford Meador has received grants from NIH/NINDS 2U01-NS038455-11A1, NIH/NINDS R01NS088748-01, Medtronics; Eisai Inc., and Sunovion Pharma; and has been a consultant for the Epilepsy Consortium, Eisai, GW Pharmaceuticals, Medtronics, NeuroPace, Novartis, Supernus, Upsher Smith Labs, UCB Pharma, and Vivus Pharma. Clinical income: EEG procedures and patient care.

Support: Interview and filming supported by Touch Medical Media. Interview conducted by Katey Gabrysch.

Filmed as a highlight of AAN Annual Virtual Meeting 2021.

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