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Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is a rare, autoimmune neurological disorder in which peripheral nerve demyelination typically results in weakness, impaired limb sensation, fatigue and pain.1–4 CIDP may adversely affect activities of daily living, with a substantial impact on functional ability and psychological well-being.2–6 Primary treatment goals are reducing symptoms, improving functional status and maintaining long-term remission.7 The […]

Martin Brodie, CONy 2020 – Combination Antiepileptic Drug Therapy

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Published Online: Dec 18th 2020

It was a pleasure to speak with Martin Brodie (President, International Bureau for Epilepsy and co-Section Head of Epilepsy for CONy), who spoke with us on the topic of the debate session he participated in: Should combination antiepileptic drug (AED) therapy be offered immediately after failure of a single antiepileptic drug?

Questions

  1. Could you tell us a little about the current standard of care and the unmet need in the treatment of epilepsy? (0:08)
  2. What evidence supports the use of combination antiepileptic drug therapy and how should it be introduced? (1:48)
  3. If combination therapy is used, how do we best optimise the outcome? (3:45)
  4. What are the potential side effects of antiepileptic drug therapy and how can they be minimised? (5:40)
  5. What other factors should be considered to optimise polytherapy in patients with epilepsy? (7:07)

Support: Interview and filming supported by Touch Medical Media Ltd.

Disclosures: Martin Brodie has nothing to disclose in relation to this video

Filmed in coverage of the 14th World Congress on Controversies in Neurology (CONy Virtual, November 2020).

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