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The prevalence of unruptured intracranial aneurysms (IAs) is approximately 3% of the population, with incidence on the rise due to the increased utilization of neuro-imaging for diverse objectives.1,2 The average risk of rupture for unruptured IA is estimated to vary from 0.3% to exceeding 15% per 5 years.3 Ruptured IA is the primary aetiology of […]

Martin Brodie, CONy 2020 – Combination Antiepileptic Drug Therapy

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Published Online: Dec 18th 2020

It was a pleasure to speak with Martin Brodie (President, International Bureau for Epilepsy and co-Section Head of Epilepsy for CONy), who spoke with us on the topic of the debate session he participated in: Should combination antiepileptic drug (AED) therapy be offered immediately after failure of a single antiepileptic drug?

Questions

  1. Could you tell us a little about the current standard of care and the unmet need in the treatment of epilepsy? (0:08)
  2. What evidence supports the use of combination antiepileptic drug therapy and how should it be introduced? (1:48)
  3. If combination therapy is used, how do we best optimise the outcome? (3:45)
  4. What are the potential side effects of antiepileptic drug therapy and how can they be minimised? (5:40)
  5. What other factors should be considered to optimise polytherapy in patients with epilepsy? (7:07)

Support: Interview and filming supported by Touch Medical Media Ltd.

Disclosures: Martin Brodie has nothing to disclose in relation to this video

Filmed in coverage of the 14th World Congress on Controversies in Neurology (CONy Virtual, November 2020).

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