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The prevalence of unruptured intracranial aneurysms (IAs) is approximately 3% of the population, with incidence on the rise due to the increased utilization of neuro-imaging for diverse objectives.1,2 The average risk of rupture for unruptured IA is estimated to vary from 0.3% to exceeding 15% per 5 years.3 Ruptured IA is the primary aetiology of […]

Pat Penovich, AES 2020 – The Patient Experience With Diazepam Nasal Spray

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Published Online: Dec 18th 2020

It was a pleasure to talk to Pat Penovich (Minnesota Epilepsy Group, St. Paul, MN, USA) about the exit survey, of a Phase 3 study, assessing patient experience of using the diazepam nasal spray for seizure clusters. The abstract ‘Examining the Patient Experience With Diazepam Nasal Spray for Seizure Clusters: Patient-reported Results From an Exit Survey of a Phase 3, Open-label, Repeat Dose Safety Study.’ was presented at the virtual AES 2020, 4-8 December 2020.

Questions

  1. What are the advantages of intranasal delivery of rescue medications compared with current options in patients with epilepsy clusters? (0:05)
  2. Could you tell us a little about the diazepam nasal spray and it’s indications? (1:36)
  3. Could you give us an overview of your recent study on patient experience with diazepam nasal spray? (2:44)
  4. What were the findings of the study and what are the implications for future clinical practice? (3:50)
  5. Which patients are most likely to benefit from the diazepam nasal spray? (5:12)

Disclosures: Consultant and on Speaker’s Bureau for Neurelis, SK and UCB; Speaker’s Bureau for Greenwich; and Consultant for Marinus and LVIS.

Support: Interview and filming supported by Touch Medical Media.

Filmed as a highlight of AES 2020, 4-8 December, 2020 (Virtual).

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