Huntington’s Disease
Watch Time: 04:11 mins

Salvatore Mazzeo, EAN 2022: Cognitive decline – challenges in diagnosis

Published Online: July 11th 2022

In this touchNEUROLOGY interview at EAN 2022, Dr Salvatore Mazzeo (University of Florence, Florence, Italy) discusses his study on HTT alleles containing from 27 to 35 CAG repeats – termed intermediate alleles (IAs) – and the effect of these IAs on progression of cognitive impairment in patients with subjective cognitive decline.

The abstract titled, Huntingtin intermediate alleles influence the progression from Subjective Cognitive Decline to Mild Cognitive Impairment (Abstract #OPR-031) took place at the European Academy of Neurology Congress 2022, 25–28 June 2022.

Questions:

1. What are the challenges in effective early diagnosis of cognitive decline? (00:13)

2. You identified several risk factors for cognitive decline; what were these? (01:39)

Disclosure: Salvatore Mazzeo has nothing to disclose in relation to this video interview.

Support: Interview and filming supported by Touch Medical Media. Interview conducted by Lisa Glass.

Filmed as a highlight of EAN 2022.

 

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